Author/Authors :
Xiong، نويسنده , , Fei and Chen، نويسنده , , Xu-Xiang and Liu، نويسنده , , Zhi-Qian and Chen، نويسنده , , Fen-Er، نويسنده ,
Abstract :
A concise and efficient TEA-mediated desymmetrization of meso-thioanhydride 6 with 5-ethoxy-5-oxopentylzinc bromine has been developed, which affords a convenient strategy for the stereospecific total synthesis of (±)-biotin 1.