Author/Authors :
Pasternak، نويسنده , , Monika and Paradowska، نويسنده , , Joanna and Rogozi?ska، نويسنده , , Maria and Mlynarski، نويسنده , , Jacek، نويسنده ,
Abstract :
A chiral prolinamide-based zinc complex promotes the aldol reaction of ketones with aqueous formaldehyde, giving the corresponding adducts in good yields and high ees. The efficient direct aldol reaction of formaldehyde with ketones in homogeneous aqueous solution is presented for the first time.
