• Title of article

    The effect of sulfur stereochemistry of l-β,β-dimethylmethionine S-oxide on the physicochemical properties of truncated polytheonamides

  • Author/Authors

    Matsuoka، نويسنده , , Shigeru and Mizoguchi، نويسنده , , Yuki and Itoh، نويسنده , , Hiroaki and Okura، نويسنده , , Ken-ichi Shinohara، نويسنده , , Naoki and Inoue، نويسنده , , Masayuki، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2010
  • Pages
    4
  • From page
    4644
  • To page
    4647
  • Abstract
    l-β,β-Dimethylmethionine S-oxide is a unique amino acid found in polytheonamides. Four designed hexapeptides containing the sulfide, (SR)-sulfoxide, (SS)-sulfoxide, and sulfone derivatives of l-dimethylmethionine were synthesized and functionally analyzed. Our results indicate that the sulfoxide stereochemistry of the peptides controls their overall physicochemical properties.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2010
  • Journal title
    Tetrahedron Letters
  • Record number

    1874319