Title of article :
Synthesis and cytotoxic evaluation of cis-locked and constrained analogues of combretastatin and combretastatin A4
Author/Authors :
Magali M. Lorion، نويسنده , , Magali and Agouridas، نويسنده , , Vangelis and Couture، نويسنده , , Axel and Deniau، نويسنده , , Eric and Grandclaudon، نويسنده , , Pierre، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Pages :
4
From page :
5146
To page :
5149
Abstract :
A series of cis-locked stilbenic compounds related to combretastatin and combretastatin A4 has been designed and synthesized. The cytotoxic effects of these rigid analogues were evaluated as well as their abilities to inhibit tubulin polymerization.
Keywords :
isoindolinones , Oxygen heterocycle , Oxidation , Anticancer agents , Combretastatins
Journal title :
Tetrahedron Letters
Serial Year :
2010
Journal title :
Tetrahedron Letters
Record number :
1874763
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1874763
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