Title of article :
Generation of pyrrolo[2,3-d]pyrimidines. Unexpected products in the multicomponent reaction of 6-aminopyrimidines, dimedone, and arylglyoxal
Author/Authors :
Quiroga، نويسنده , , Jairo and Acosta، نويسنده , , Paola A. and Cruz، نويسنده , , Silvia and Abonيa، نويسنده , , Rodrigo and Insuasty، نويسنده , , Braulio and Nogueras، نويسنده , , Manuel and Cobo، نويسنده , , Justo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
A series of 6-aryl-5-(1-cyclohexen-1-yl)pyrrolo[2,3-d]pyrimidines 9a–q were obtained by the three-component reaction between 6-aminopyrimidines 6, 7, 8, dimedone 2, and arylglyoxal 5a,b. The unexpected cyclization process was established by NMR and X-ray diffraction measurements.
Keywords :
multicomponent reaction , Aminopyrimidines , Arylglyoxal , Pyrrolopyrimidines , Dimedone
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
