Author/Authors :
Jalani، نويسنده , , Hitesh B. and Kaila، نويسنده , , Jitendra C. and Baraiya، نويسنده , , Arshi B. and Pandya، نويسنده , , Amit N. and Sudarsanam، نويسنده , , V. and Vasu، نويسنده , , Kamala K.، نويسنده ,
Abstract :
Here, we report a versatile multicomponent synthesis of novel quinazolinon-2-yl-tetrasubstituted thiophenes by a one-pot reaction using different alkyl-3-aminobutenoates, isothiocyanates and 2-halomethyl quinazolinones in good to excellent yields. The reaction probably proceeds by an intramolecular 5-exo-trig cyclisation.
Keywords :
Quinazolinon-2-yl-tetrasubstituted thiophenes , Alkyl-3-aminobutenoates , Isothiocyanates , 5-exo-trig