Title of article
An organocatalytic route to the synthesis of lactone moiety of compactin and mevinolin
Author/Authors
Kumar، نويسنده , , Pradeep and Pandey، نويسنده , , Menaka and Gupta، نويسنده , , Priti and Dhavale، نويسنده , , Dilip D.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
2
From page
5838
To page
5839
Abstract
An efficient synthesis of lactone moiety of compactin has been achieved. The stereogenic centers were generated by means of iterative proline-catalyzed sequential α-aminoxylation and Horner–Wadsworth–Emmons (HWE) olefination of aldehydes.
Keywords
lactone , proline , organocatalysis , Compactin , Aminoxylation
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1875319
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