Title of article :
Synthesis and single crystal X-ray analysis of two griseofulvin metabolites
Author/Authors :
Rّnnest، نويسنده , , Mads H. and Harris، نويسنده , , Pernille and Gotfredsen، نويسنده , , Charlotte H. and Larsen، نويسنده , , Thomas O. and Clausen، نويسنده , , Mads H.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
The two phenols, 6-O-desmethyl griseofulvin and 4-O-desmethyl griseofulvin are metabolites of the antifungal drug griseofulvin. Herein, we present an improved synthesis of the 6-phenol derivative, and an unequivocal proof of both structures by single-crystal X-ray analysis.
Keywords :
griseofulvin , X-ray structures , Synthesis , metabolites
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
