Author/Authors :
Shimizu، نويسنده , , Ryo and Egami، نويسنده , , Hiromichi and Nagi، نويسنده , , Tatsuya and Chae، نويسنده , , Jungha and Hamashima، نويسنده , , Yoshitaka and Sodeoka، نويسنده , , Mikiko، نويسنده ,
Abstract :
Direct C2-selective trifluoromethylation of indole derivatives was achieved with Togni’s hypervalent iodine reagent and CuOAc as a catalyst in MeOH under mild conditions, affording the desired C2-trifluoromethylated indoles in good yield (up to 90%).
Keywords :
trifluoromethylation , indole , Catalysis , regioselective
