Title of article :
Synthesis of 2,3-dihydro-1,4-dithiinyl nucleosides via Pummerer-type glycosidation
Author/Authors :
Paolella، نويسنده , , Concetta and D’Alonzo، نويسنده , , Daniele and Guaragna، نويسنده , , Annalisa and Cermola، نويسنده , , Flavio and Palumbo، نويسنده , , Giovanni، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
A straightforward procedure for the preparation of nucleoside analogue 1 and its regioisomer 2 containing a dihydro-1,4-dithiin as sugar moiety has been accomplished in four steps by our readily available heterocyclic system 5. Nucleobase insertion was carried out by direct addition of N4-acetylcytosine to sulfoxide derivatives via Pummerer-type glycosidation reaction.
Keywords :
Heterocyclic nucleosides , Dithiins , Nucleoside analogues , Pummerer-type glycosidation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
