Author/Authors :
Tatyana E. Glotova، نويسنده , , Tatyana E. and Schmidt، نويسنده , , Elena Yu. and Dvorko، نويسنده , , Marina Yu. and Ushakov، نويسنده , , Igor’ A. and Mikhaleva، نويسنده , , Al’bina I. and Trofimov، نويسنده , , Boris A.، نويسنده ,
Abstract :
О-2-(Acyl)vinylketoximes (freshly prepared from ketoximes and acylacetylenes in the presence of Ph3P as catalyst in up to 83% yields) rearrange upon heating (125–150 °C) to give 2- or 3-acylpyrroles, wherein the positions of the acyl substituents do not correspond to known O-vinyloxime rearrangements; the chemo- and regioselectivity of the rearrangements depend on the reaction conditions. The described rearrangement enables syntheses of previously inaccessible substituted 2- or 3-acylpyrroles.
