Title of article
Escherichia coli BioH: a highly enantioselective and organic solvent tolerant esterase for kinetic resolution of sec-alcohols
Author/Authors
Wang، نويسنده , , Bo and Tang، نويسنده , , Xiaoling and Liu، نويسنده , , Ji and Yu، نويسنده , , Hongwei، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
5
From page
6360
To page
6364
Abstract
Escherichia coli BioH, which is obligatory for biotin synthesis, was found to be an organic solvent tolerant esterase with high enantioselectivity for the kinetic resolution of sec-alcohols using free enzyme powder. With this esterase, a variety of racemic sec-alcohols were efficiently resolved with ee values of up to 99%.
Keywords
Escherichia coli BioH , kinetic resolution , esterase , Enantioselectivity , organic solvent tolerance
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1875753
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