Title of article
The traceless Staudinger ligation with fluorine-18: a novel and versatile labeling technique for the synthesis of PET-radiotracers
Author/Authors
Pretze، نويسنده , , Marc and Wuest، نويسنده , , Frank and Peppel، نويسنده , , Tim and Kِckerling، نويسنده , , Martin and Mamat، نويسنده , , Constantin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
5
From page
6410
To page
6414
Abstract
The development of rapid radiolabeling techniques under mild reaction conditions involving the short-lived positron emitter fluorine-18 remains a special challenge in organic PET chemistry. This work describes a novel and facile application of the traceless Staudinger ligation as a mild and versatile labeling method for preparation of various radiotracers labeled with fluorine-18.
Keywords
Traceless Staudinger ligation , Fluorine-18 , Bioorthogonal , Radiolabeling
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1875785
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