Title of article :
Silica-immobilized piperazine: A sustainable organocatalyst for aldol and Knoevenagel reactions
Author/Authors :
Shanmuganathan، نويسنده , , Saravanakumar and Greiner، نويسنده , , Lasse and Domيnguez de Marيa، نويسنده , , Pablo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
Silica-supported piperazine was found to be an efficient catalyst for aldol reactions of aromatic aldehydes and ketones with straightforward product isolation and catalyst reuse. Furthermore, the catalyst is active in Knoevenagel-type reactions to afford coumarin derivatives, using 2-methyltetrahydrofuran (2-MeTHF) as a novel bio-based solvent.
Keywords :
Sustainable chemistry , Piperazine , Knoevenagel condensation , aldol reaction , Immobilized organocatalyst , 2-Methyltetrahydrofuran
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
