Title of article
Efficient synthesis of highly functionalized vinylogous thiol esters
Author/Authors
Liu، نويسنده , , Jinglin and Xu، نويسنده , , Xianxiu and Li، نويسنده , , Dongwei and Zhang، نويسنده , , Lei and Zhang، نويسنده , , Kun and Liu، نويسنده , , Qun، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
6918
To page
6920
Abstract
A series of vinylogous thiol esters 2, 3 and 2,6-dioxo-1,2,5,6-tetrahydropyridines (cyclic vinylogous thiol esters) 4 were prepared in high to excellent yields from the tandem reaction of readily available α-alkenoylketene diethylthioacetals 1 and diethyl malonate. A plausible mechanism, which involves a base catalyzed retro-Michael ring opening of cyclohexanenes 2 to give vinylogous thiol ester 3, is disclosed.
Keywords
Vinylogous thiol esters , ?-Alkenoylketene diethylthioacetals , Diethyl malonate , Michael addition , retro-Michael addition
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1876186
Link To Document