Title of article
An unexpected rearrangement of the benzofurobenzazepine skeleton of galanthamine-type alkaloids
Author/Authors
Herke، نويسنده , , Klلra and Hazai، نويسنده , , Lلszlَ and Sلnta، نويسنده , , Zsuzsanna and Dubrovay، نويسنده , , Zsَfia and Hلda، نويسنده , , Viktor and Szلntay Jr.، نويسنده , , Csaba and Kalaus، نويسنده , , Gyِrgy and Szلntay، نويسنده , , Csaba، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
6932
To page
6934
Abstract
Attempted cyclisation of N-methylated spiro benzazepine–cyclohexenone (5) into the corresponding N-methyl tetracyclic unit of galanthamine-type alkaloids (6) instead gave an unexpected rearrangement to yield a cyclopentanoisoquinolinone derivative (7). Methylation of the tetrahydrobenzofurobenzazepine tetracycle resulted in the expected N-methyl derivative 6, and the anomalous product 8, with structure similar to that of 7.
Keywords
Cyclopentanoisoquinolinone , Amaryllidaceae alkaloids , Spirocyclohexenone , Rearrangement
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1876199
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