Title of article :
Ceric ammonium nitrate-mediated detritylation of tritylated amines
Author/Authors :
Pattanayak، نويسنده , , Sankha and Sinha، نويسنده , , Surajit، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Efficient deprotection of tritylated amines to the corresponding amines mediated by 20 mol % ceric ammonium nitrate [Ce(NH4)2(NO3)6, CAN], 10 equiv of acetic acid and 15 equiv of water in dichloromethane is presented. This method equally worked well in the case of morpholino nucleosides.
Keywords :
Trityl deprotection , ceric ammonium nitrate , Morpholino nucleosides , Cerium(III) EPR , Deprotection mechanism
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
