Title of article
Novel cytotoxic constituents of Orthosiphon diffusus
Author/Authors
Holla، نويسنده , , Harish and Srinivas، نويسنده , , Yallamalla and Majhi، نويسنده , , Anjoy and Srinivasulu، نويسنده , , Gannoju and Sridhar، نويسنده , , Balasubramanian and Krishna، نويسنده , , Arepalli Sai and Rao، نويسنده , , Janapala Venkateswara and Das، نويسنده , , Biswanath، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
49
To page
52
Abstract
Chemical investigation on Orthosiphon diffusus resulted in the isolation of four relatively rare, novel polychiral furanopyrans, orthodiffenes A–D (1–4) which were characterized from detailed studies of their 1D and 2D NMR spectra. The X-ray crystallographic analysis of orthodiffene A (1) was accomplished. The in vitro cytotoxic activity of orthodiffenes A–C (1–3) was tested against Jurkat and HL-60 cells using camptothecin as a positive control. Orthodiffenes A (1) and B (2) showed comparable activity to camptothecin against HL-60 and Jurkat cells, respectively.
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1876248
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