• Title of article

    Synthesis and potent cytotoxic activity of 8- and 9-anilinophenanthridine-7,10-diones

  • Author/Authors

    Bernardo، نويسنده , , Paul H. and Khanijou، نويسنده , , Jasmeet K. and Lam، نويسنده , , Tze Hau and Tong، نويسنده , , Joo Chuan and Chai، نويسنده , , Christina L.L.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2011
  • Pages
    3
  • From page
    92
  • To page
    94
  • Abstract
    A series of 8-anilino and 9-anilinophenanthridine-7,10-diones was prepared and screened against various cancer cell lines to measure anti-proliferative activity. The compounds tested display potent cytotoxic activity in the micromolar and sub-micromolar range. These compounds are promising new leads for developing anticancer compounds.
  • Keywords
    Anticancer , Michael addition , SRB assay , quinones
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2011
  • Journal title
    Tetrahedron Letters
  • Record number

    1876285