Title of article
Synthesis of C-9 oxidised N-acetylneuraminic acid derivatives as biological probes
Author/Authors
Kiefel، نويسنده , , Milton J. and Chopra، نويسنده , , Pradeep and Madge، نويسنده , , Paul D. and Szyczew، نويسنده , , Alex and Thomson، نويسنده , , Robin J. and Grice، نويسنده , , I. Darren and von Itzstein، نويسنده , , Mark، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
98
To page
100
Abstract
Sialic acids are 9-carbon acidic sugars involved in a number of important biological processes and human diseases. As part of our ongoing interest in the development of novel sialic acids as biological probes, we have developed an efficient and simple synthesis of C-9 oxidised sialic acid derivatives. The key oxidative step involves the use of TEMPO under carefully controlled aqueous pH conditions.
Keywords
Biological probes , carbohydrates , Sialic acid , Oxidation , Chain-extended
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1876294
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