Author/Authors :
McClean، نويسنده , , Kathleen and Preston، نويسنده , , Christopher and Spence، نويسنده , , David and Sutton، نويسنده , , Peter W. and Whittall، نويسنده , , John، نويسنده ,
Abstract :
Proof-of-concept has been demonstrated for the biocatalytic transformation of aciclovir into valaciclovir, attaining high conversions from a solid-to-solid biotransformation in l-valine methyl ester using various formulations of Subtilisin Carlsberg activated for use in organic solvent.
