Title of article
4-Chloro-3-(trifluoroacetyl)coumarin as a novel building block for the synthesis of 7-(trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones
Author/Authors
Iaroshenko، نويسنده , , Viktor O. and Ali، نويسنده , , Sajid and Babar، نويسنده , , Tariq Mahmood and Dudkin، نويسنده , , Sergii and Mkrtchyan، نويسنده , , Satenik and Rama، نويسنده , , Nasim Hasan and Villinger، نويسنده , , Alexander and Langer، نويسنده , , Peter، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
373
To page
376
Abstract
4-Chloro-3-(trifluoroacetyl)coumarin was synthesized for the first time via direct TMSCl-mediated acylation of 4-hydroxycoumarin with TFAA followed by the treatment with POCl3. The reaction of 4-chloro-3-(trifluoroacetyl)coumarin with commercially available anilines is a two-step method, which affords a set of 7-(trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones in good to excellent yields.
Keywords
Anilines , fluorine , coumarins , Heterocycles , 3-b]quinolines , cyclization
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1876494
Link To Document