Author/Authors :
Iaroshenko، نويسنده , , Viktor O. and Ali، نويسنده , , Sajid and Babar، نويسنده , , Tariq Mahmood and Dudkin، نويسنده , , Sergii and Mkrtchyan، نويسنده , , Satenik and Rama، نويسنده , , Nasim Hasan and Villinger، نويسنده , , Alexander and Langer، نويسنده , , Peter، نويسنده ,
Abstract :
4-Chloro-3-(trifluoroacetyl)coumarin was synthesized for the first time via direct TMSCl-mediated acylation of 4-hydroxycoumarin with TFAA followed by the treatment with POCl3. The reaction of 4-chloro-3-(trifluoroacetyl)coumarin with commercially available anilines is a two-step method, which affords a set of 7-(trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones in good to excellent yields.
Keywords :
Anilines , fluorine , coumarins , Heterocycles , 3-b]quinolines , cyclization
