Author/Authors :
Chavan، نويسنده , , Subhash P. and Dumare، نويسنده , , Nilesh B. and Harale، نويسنده , , Kishor R. and Kalkote، نويسنده , , Uttam R.، نويسنده ,
Abstract :
A synthetic route to (2S,3S)-3-hydroxypipecolic acid was achieved from readily available nonchiral pool starting material cis-2-butene-1,4-diol and involved Claisen orthoester rearrangement, Sharpless asymmetric dihydroxylation and intramolecular lactamisation of azido lactone as the key steps.