Author/Authors :
Kanouni، نويسنده , , Toufike and Dong، نويسنده , , Qing and Abelovski، نويسنده , , Benjamin and Wallace، نويسنده , , Michael B.، نويسنده ,
Abstract :
A novel, efficient route for the synthesis of 1,8-naphthyridine-2,5-dione compounds is reported. The synthetic scheme allows for diversification at the 4-position of the core, and it was utilized to develop a series of inhibitors for MEK kinase.
