Author/Authors :
Epifano، نويسنده , , Francesco and Genovese، نويسنده , , Salvatore and Rosati، نويسنده , , Ornelio and Tagliapietra، نويسنده , , Silvia and Pelucchini، نويسنده , , Caroline and Curini، نويسنده , , Massimo، نويسنده ,
Abstract :
Ytterbium triflate was shown to be effective in promoting the synthesis of substituted indole derivatives starting from indole, aldehydes, and dimethyl malonate by a Yonemitsu-type three component reaction. The whole process was carried out in solvent-free conditions and furnished the desired adducts in 42–67% yield.
Keywords :
Heterogeneous catalysis , Indole derivatives , multicomponent reactions , Yonemitsu-type reaction , ytterbium triflate
