Title of article
Synthesis of benzo-, pyrido-, thieno- and imidazo-fused N-hydroxy-4-oxopyrimidine-2-carboxylic acid derivatives
Author/Authors
Bosch، نويسنده , , Lluيs and Mouscadet، نويسنده , , Jean-François and Ni، نويسنده , , Xio-Ju and Vilarrasa، نويسنده , , Jaume، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
753
To page
756
Abstract
N-Hydroxy-4-oxoquinazoline-2-carboxamide derivatives (cyclic hydroxamic acids) and related pyrido- and thieno-substituted analogues, as well as a N-hydroxyhypoxanthine-2-carboxamide were synthesised for the first time, by means of a four-step sequence that involves a smooth reaction of aminohydroxamates with methyl trimethoxyacetate. Other strategies were unsuccessful.
Keywords
Methyl trimethoxyacetate , Fused N-hydroxypyrimidin-4-ones , amidation of esters
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1876801
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