Title of article :
Intramolecular copper(I)-catalyzed 1,3-dipolar cycloaddition of azido-alkynes: synthesis of triazolo-benzoxazepine derivatives and their biological evaluation
Author/Authors :
Chandrasekhar، نويسنده , , Srivari and Seenaiah، نويسنده , , Mallikanti and Kumar، نويسنده , , Abhishek and Reddy، نويسنده , , Chada Raji and Mamidyala، نويسنده , , Suman Kumar and Kumar، نويسنده , , Chityal Ganesh and Balasubramanian، نويسنده , , Sridhar، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Synthesis of a series of [1,2,3] triazolo [5,1-c] [1,4]benzoxazepine derivatives have been accomplished by the intramolecular Cu(I)-catalyzed cycloaddition of azido-alkynes derived from salicylaldehyde. The biological profile of these heterocyclic structural scaffolds toward anti-bacterial as well as anti-fungal activity has also been illustrated.
Keywords :
1 , 3-dipolar cycloaddition , Triazolo-benzoxazepine , anti-microbial , click chemistry , Copper-catalysis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
