Title of article :
Syntheses of the opioid substructures 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine and 2,3,4,5-tetrahydro-1,5-methano-1H-2-benzazepine
Author/Authors :
Coe، نويسنده , , Jotham W. and Brooks، نويسنده , , Paige R. and Vetelino، نويسنده , , Michael G. and Bashore، نويسنده , , Crystal G. and Bianco، نويسنده , , Krista and Flick، نويسنده , , Andrew C.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Concise syntheses of 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine (12) and 2,3,4,5-tetrahydro-1,5-methano-1H-2-benzazepine (18) are described and involve an intramolecular Friedel–Crafts alkylation and an intramolecular Heck cyclization as their respective key ring-forming steps.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
