Author/Authors :
Liusheng and Vimolratana، نويسنده , , Marc and Simard، نويسنده , , Jillian L. and Brown، نويسنده , , Sean P.، نويسنده ,
Abstract :
A mild and efficient Pd-catalyzed coupling of amides with 2-chloropyrimidines is described. The use of bidentate phosphines, such as Xantphos (7), as supporting ligands was found to be crucial for providing high yields of 2-(N-acylamino)pyrimidine coupling products 1.
