Title of article
Studies on the epimerization of diastereomeric lactides
Author/Authors
Ivan A. Shuklov، نويسنده , , Ivan A. and Jiao، نويسنده , , Haijun and Schulze، نويسنده , , Joachim and Tietz، نويسنده , , Wolfgang and Kühlein، نويسنده , , Klaus and Bِrner، نويسنده , , Armin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
1027
To page
1030
Abstract
The epimerization of chiral lactides was studied in the presence of various homogeneous and heterogeneous bases. Some solvent/base systems were found to promote epimerization at room temperature efficiently. Side reactions such as polymerization were not observed or occurred only slowly. This new protocol offers the opportunity of the transformation of meso-lactide into rac-lactide. Therefore it can reduce the overall manufacturing costs of polylactides, a problem which currently hampers the broad application of those environmentally friendly polymers in a large scale.
Keywords
Stereospecific polymers , lactide , Isomerization , Stereoisomers , Poly-lactic acid
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877028
Link To Document