Title of article
Synthesis of 6- and 7-propargyloxy derivatives of 4-(3-fluoroanilino)-quinazoline
Author/Authors
Pham، نويسنده , , Helen Trinh and Hanson، نويسنده , , Robert N. and Olmsted، نويسنده , , Sandra L. and Kozhushnyan، نويسنده , , Anton and Visentin، نويسنده , , Adam and Weglinsky، نويسنده , , Paul J. and Massero، نويسنده , , Chris and Bailey، نويسنده , , Kristen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
1053
To page
1056
Abstract
The preparation of the novel isomeric 6- and 7-propargyloxy derivatives of 4-(3-fluoroanilino)-quinazoline was achieved using a six-step process. An alternate method to the 7-propargyloxy derivative and analogous 7-propargyloxy containing compounds is also described.
Keywords
Anilinoquinazoline , Tyrosine kinase inhibitors , Bifunctional derivatives
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877048
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