Title of article
Arylation of [6,6]-spiroacetal enol ethers: reactivity and rearrangement
Author/Authors
Aumann، نويسنده , , Kylee M. and Healy، نويسنده , , Peter C. and Coster، نويسنده , , Mark J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
1070
To page
1073
Abstract
Attempts to selectively arylate [6,6]-spiroacetal enol ethers at the 2-position delivered unexpected results. Palladium-mediated arylation conditions afforded the double-Heck product, whereas reaction with benzenesulfinic acid resulted in a facile rearrangement into the corresponding 5-phenylsulfonyl-3,4,5,6-tetrahydrochromans, providing access to 5-aryl-3,4,5,6-tetrahydrochroman and hexahydrochroman derivatives.
Keywords
Tetrahydrochroman , Enol ether , Rearrangement , spiroacetal , Hexahydrochroman
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877059
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