Title of article
A simple and efficient large-scale synthesis of 3-hydroxyphthalans via oxa-Pictet–Spengler reaction catalyzed by nanosilica sulfuric acid
Author/Authors
Khorsandi، نويسنده , , Zahra and Khosropour، نويسنده , , Ahmad Reza and Mirkhani، نويسنده , , Valiollah and Mohammadpoor-Baltork، نويسنده , , Iraj and Moghadam، نويسنده , , Majid and Tangestaninejad، نويسنده , , Shahram، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
1213
To page
1216
Abstract
Nanosilica sulfuric acid is found to be a new, powerful and reusable heterogeneous catalyst for the rapid synthesis of 3-hydroxyphthalans via condensation of aromatic aldehydes and 3-hydroxybenzyl alcohols under conventional heating and microwave irradiation. Scale-up preparation of these heterocycles is also carried out.
Keywords
Phthalans , Nanosilica sulfuric acid , 3-Hydroxybenzyl alcohol , Aryl aldehyde , microwave irradiation , oxa-Pictet–Spengler reaction
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877172
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