• Title of article

    Z-Selective intramolecular Horner–Wadsworth–Emmons reaction for the synthesis of macrocyclic alkenes

  • Author/Authors

    Ando، نويسنده , , Kaori and Sato، نويسنده , , Kaori، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2011
  • Pages
    4
  • From page
    1284
  • To page
    1287
  • Abstract
    The Z-selective intramolecular Horner–Wadsworth–Emmons reaction of the substrates 7–12 (RO)2P(O)CHR′CO2Et (R′ = (CH2)nCHO) (R = Ph or o-tBuC6H4) gives the 13–18-membered cyclic alkenes selectively (up to Z:E = 97:3) in good yields using NaH in THF under high dilution conditions.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2011
  • Journal title
    Tetrahedron Letters
  • Record number

    1877220