Author/Authors :
Mangette، نويسنده , , John E. and Chen، نويسنده , , Xuemei and Krishnamoorthy، نويسنده , , Ravi and Samuel Vellekoop، نويسنده , , A. and Csakai، نويسنده , , Adam J. and Camara، نويسنده , , Fatoumata and Paquette، نويسنده , , William D. and Wang، نويسنده , , Hong-Jun and Takahashi، نويسنده , , Hidenori and Fleck، نويسنده , , Roman and Roth، نويسنده , , Gregory P.، نويسنده ,
Abstract :
A three-step method was developed to convert N-1 unprotected 3-substituted indoles to 3-substituted 2-acylaminoindoles. Established indole chlorination chemistry was employed to generate stable 2-trifluoroacetylamino indoles, which were subsequently deprotected and selectively acylated.
Keywords :
Acylaminoindole , 2-Aminoindole acylation , 2-Aminoindole , Chloroindolenine
