Author/Authors :
Naskar، نويسنده , , Subhendu and Banerjee، نويسنده , , Maitreyee and Hazra، نويسنده , , Abhijit and Mondal، نويسنده , , Shyamal and Maity، نويسنده , , Arindam and Paira، نويسنده , , Rupankar and Sahu، نويسنده , , Krishnendu B. and Saha، نويسنده , , Pritam and Banerjee، نويسنده , , Sukdeb and Mondal، نويسنده , , Nirup B.، نويسنده ,
Abstract :
A high yielding environmentally benign protocol has been developed for the synthesis of pyrrolo[2,1-a]isoquinoline using chromone-3-carboxaldehyde, isoquinoline and phenacyl bromide/bromoacetic acid ester as reagents in aqueous micellar medium. The method is operationally simple and more effective compared to the previous methods in terms of the yield of the products as well as the reaction time.
Keywords :
Chromone-3-carboxaldehyde , 1-a]isoquinoline , 1 , 3-Dipolar cycloaddition reaction , reactions in water , Micelle