Title of article
Asymmetric α-2-tosylvinylation of in situ-generated N-2-tosylvinyl proline-derived ammonium ylides
Author/Authors
Igarashi، نويسنده , , Tomohito and Tayama، نويسنده , , Eiji and Iwamoto، نويسنده , , Hajime and Hasegawa، نويسنده , , Eietsu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
1819
To page
1821
Abstract
Asymmetric α-2-tosylvinylation of N-substituted proline esters using ethynyl tolyl sulfone as an electrophile was shown to proceed in good yield with high enantioselectivities without the addition of any bases. The reaction proceeds via the formation of N-2-tosylvinyl ammonium ylides.
Keywords
Ylide , asymmetric synthesis , Amino acid , Zwitterion
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877636
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