Title of article
Demonstration of 14–20-membered intramolecular carbonyl ylides: diastereoselective synthesis of macrocycles incorporating spiro-indolooxiranes
Author/Authors
Muthusamy، نويسنده , , Sengodagounder and Karikalan، نويسنده , , Thangaraju and Suresh، نويسنده , , Eringathodi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
1934
To page
1937
Abstract
A range of macrocycles (13–19-membered) possessing spiro-indolooxirane unit were synthesized with complete diastereoselectivity in good yield by the rhodium(II) acetate catalyzed reaction of substituted cyclic diazoamides in dry dichloromethane. The reaction proceeds via the formation of the corresponding macrocyclic carbonyl ylide followed by a con-rotatory electrocyclization process.
Keywords
Carbonyl ylide , Diazoamide , macrocycle , Spiro-indolooxirane , Rhodium acetate
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877716
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