Title of article :
An efficient methodology to substituted furans via oxidation of functionalized α-diazo-β-ketoacetates
Author/Authors :
Truong، نويسنده , , Phong and Xu، نويسنده , , Xinfang and Doyle، نويسنده , , Michael P.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
DMDO oxidation of functionalized α-diazo-β-ketoacetates, formed by zinc triflate catalyzed Mukaiyama-aldol condensation of methyl diazoacetoacetate with aldehydes, occurred in quantitative yield to form dihydrofuranols that undergo acid catalyzed dehydration under mild conditions to generate 3-methoxyfuran-2-carboxylates in good yield.
Keywords :
diazoacetate , Vicinal-tricarbonyl , Dimethyldioxirane , furan , Oxidation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
