Title of article
Aza-Nazarov cyclization cascades
Author/Authors
Sai، نويسنده , , Kiran Kumar Solingapuram and O’Connor، نويسنده , , Matthew J. and Klumpp، نويسنده , , Douglas A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
2195
To page
2198
Abstract
Benzamides with tethered acetal groups undergo reactions in CF3SO3H to give ring-fused isoindolinones by a cyclization cascade. The reaction initially forms an N-acyliminium ion which then gives the isoindolinone by the aza-Nazarov reaction. An unusual variant also cyclizes at the allylic position.
Keywords
Heterocycles , Aza-Nazarov , N-Acyliminum ions , Superacid , cyclization
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877876
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