Title of article :
Aza-Nazarov cyclization cascades
Author/Authors :
Sai، نويسنده , , Kiran Kumar Solingapuram and O’Connor، نويسنده , , Matthew J. and Klumpp، نويسنده , , Douglas A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Benzamides with tethered acetal groups undergo reactions in CF3SO3H to give ring-fused isoindolinones by a cyclization cascade. The reaction initially forms an N-acyliminium ion which then gives the isoindolinone by the aza-Nazarov reaction. An unusual variant also cyclizes at the allylic position.
Keywords :
Heterocycles , Aza-Nazarov , N-Acyliminum ions , Superacid , cyclization
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
