Title of article
A practical and inexpensive ‘convertible’ isonitrile for use in multicomponent reactions
Author/Authors
Le، نويسنده , , Hoang V. and Fan، نويسنده , , Lijun and Ganem، نويسنده , , Bruce، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
2209
To page
2211
Abstract
N-tert-Butylamides are readily converted into the corresponding carboxylic acids by simple nitrosation. The process, which occurs under mild nonaqueous conditions, leaves carboxylic esters untouched and transforms multicomponent reaction products into useful building blocks for further synthetic elaboration.
Keywords
Isonitrile-based multicomponent reactions , t-Butylisonitrile , Carboxyl protecting group , Combinatorial chemistry , Amides to acids
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877886
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