Title of article
NMR studies of the reversible and regioselective lactonization of α-2,8-linked trisialic acid in aqueous acid
Author/Authors
Eckert، نويسنده , , Timothy K. Lu، نويسنده , , Chun-Ping and Chen، نويسنده , , Chien-Sheng and Wu، نويسنده , , Shih-Hsiung and Gervay-Hague، نويسنده , , Jacquelyn، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
2250
To page
2253
Abstract
The pH dependent lactonization of trisialic acid was examined using NMR and CE techniques. The combined studies indicate that lactonization is a dynamic, pH dependent process that occurs with preferential lactonization between the carbonyl of the central residue and the reducing end C-9 hydroxyl group.
Keywords
Nuclear magnetic resonance , Capillary electrophoresis , Sialic acid , Lactonization , regioselectivity
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877919
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