Author/Authors :
Saito، نويسنده , , Yoshio and Shinohara، نويسنده , , Yuta and Ishioroshi، نويسنده , , Shinya and Suzuki، نويسنده , , Azusa and Tanaka، نويسنده , , Makiko and Saito، نويسنده , , Isao، نويسنده ,
Abstract :
The synthesis and photophysical property of novel solvatochromic pyrene derivative, Apa 5 and fluorescent guanine ApaG 8 were described. These newly synthesized fluorescent pyrene derivatives exhibited solvent polarity dependent fluorescence at longer wavelengths. Such environmentally sensitive pyrene derivatives can be used as a reporter probe that is sensitive to the changes in the microenvironment around DNA either in vitro or in vivo.
