Title of article :
Convenient preparation of α-bromo-α-fluoro-β-hydroxyesters building blocks from aldehydes, ketones and lactones
Author/Authors :
Zoute، نويسنده , , Ludivine and Lemonnier، نويسنده , , Gérald and Nguyen، نويسنده , , Tanh Mai and Quirion، نويسنده , , Jean-Charles and Jubault، نويسنده , , Philippe، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A Reformatsky-type addition of ethyl dibromofluoroacetate associated with diethylzinc to various carbonyl compounds is described. Aldehydes, ketones and lactones were converted into the corresponding α-bromo-α-fluoro-β-hydroxyesters in good yields.
Keywords :
Reformatsky addition , Diethylzinc , carbonyl compounds , Lactones , Ethyldibromofluoroacetate
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
