Title of article :
Borinic acid catalyzed α-addition to isocyanide with aldehyde and water
Author/Authors :
Soeta، نويسنده , , Takahiro and Kojima، نويسنده , , Yuuki and Ukaji، نويسنده , , Yutaka and Inomata، نويسنده , , Katsuhiko، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A first example of diphenylborinic acid catalyzed α-addition to isocyanide with aldehyde and water is described. The reaction proceeded smoothly in the presence of water and 5 mol % of borinic acid to give the corresponding α-hydroxyamides in good to high yields. A wide range of aldehydes and isocyanides are applicable to this reaction.
Keywords :
?-Addition , Borinic acid catalyzed reaction , isocyanide , Passerini-type reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
