Title of article
Catalyst-free synthesis of octahydroacridines using glycerol as recyclable solvent
Author/Authors
Nascimento، نويسنده , , José E.R. and Barcellos، نويسنده , , Angelita M. and Sachini، نويسنده , , Maraيsa and Perin، نويسنده , , Gelson and Lenardمo، نويسنده , , Eder J. and Alves، نويسنده , , Diego and Jacob، نويسنده , , Raquel G. and Missau، نويسنده , , Fabiana، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
2571
To page
2574
Abstract
We describe herein the use of glycerol as an efficient, safe and recyclable solvent in the one-pot hetero-Diels–Alder (HDA) reaction of (R)-citronellal with substituted arylamines. The catalyst-free reactions proceed easily using glycerol at 90 °C and the corresponding octahydroacridines (OHAs) were obtained in good to excellent yields by simply decantation of products. After removing the products, glycerol was directly reused for further HDA reactions without lost of activity.
Keywords
Glycerol , Citronellal , Octahydroacridines
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878155
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