Title of article
Synthesis of resorcin[4]arene bearing self-folding substituent
Author/Authors
Enmi، J. نويسنده , , Yoshinori and Kobayashi، نويسنده , , Kazuhiro and Konishi، نويسنده , , Hisatoshi and Morimoto، نويسنده , , Minoru، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
3367
To page
3370
Abstract
Thiomethylation of resorcin[4]arene using N,N-diisopropyl-2-aminoethanethiol hydrochloride and formaldehyde [1:4:4 molar ratio] carried out in methanol/acetic acid [1:1 v/v] at 60 °C produced monofunctionalized product 3 in 68% yield. The introduced substituent was intramolecularly self-included into the cavity. This self-inclusion reduced the reactivity of the aromatic rings and inhibited further functionalization.
Keywords
Thiomethylation , Self-inclusion , Monofunctionalization
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878617
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