Author/Authors :
Roberts، نويسنده , , Bryan and Liptrot، نويسنده , , David and Luker، نويسنده , , Tim and Stocks، نويسنده , , Michael J. and Barber، نويسنده , , Catherine L. Webb، نويسنده , , Nicola and Dods، نويسنده , , Robert and Martin، نويسنده , , Barrie، نويسنده ,
Abstract :
A new, efficient and practical synthesis of quinazolin-4(3H)-ones is reported via molybdenum-mediated cyclocarbonylation using microwave irradiation. These methods allow access to a wide range of quinazolin-4(3H)-ones in reasonable yields without the need for gaseous carbon monoxide and palladium catalysts. A range of reactions illustrating the wide scope of this chemistry was carried out and all proceeded in reasonable yields.
Keywords :
Microwave chemistry , Carbodiimides , Quinazolin-4(3H)-ones , cyclocarbonylation , Molybdenum-mediated
