Title of article
Highly selective fluorescence turn-on probe for glutathione
Author/Authors
Lim، نويسنده , , Sooyeon and Lee، نويسنده , , Sanghee and Park، نويسنده , , Seung-Bum and Kim، نويسنده , , Hae-Jo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
3902
To page
3904
Abstract
An activated coumarin-3-phenyl enone (1) by an intramolecular hydrogen bond has shown a selective and ratiometric response toward GSH and Cys over other natural amino acids through the Michael addition reaction of a thiol group to 1. When GSH was added to 1, a prominent color change together with a fluorescence turn-on property was observed so that submillimolar GSH was detectable.
Keywords
Michael addition , Hydrogen bond , fluorescence , GSH
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878841
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