• Title of article

    Facile two-step synthesis of crispine A and harmicine by cyclopropylimine rearrangement

  • Author/Authors

    Saha، نويسنده , , Sanjay and Venkata Ramana Reddy، نويسنده , , Ch. and Patro، نويسنده , , Balaram، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2011
  • Pages
    3
  • From page
    4014
  • To page
    4016
  • Abstract
    The synthesis of 4 and 8 is reported. These intermediates are obtained by a one-pot tandem cyclization of 1 and 6, respectively, via Bischler Napieralski reaction followed by cyclopropylimine rearrangement. Compounds 4 and 8 were reduced by sodium borohydride in methanol to afford cytotoxic alkaloid (±)-crispine A and antileishmania compound (±)-harmicine.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2011
  • Journal title
    Tetrahedron Letters
  • Record number

    1878891